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New drug warning: Xylazine mixed in fentanyl

Adair County's WATCH (working actively toward community health) Coalition met for interagency information sharing on September 14, 2013.

Updates included a new drug warning from Adanta alerting providers to the risks of xylazine, a non-opioid agent increasingly being found in combination with opioids such as fentanyl. Xylazine, which has not been approved by the FDA for use in humans, can cause severe circulatory changes with devastating effects on human tissue leading to painful open lesions, necrosis, and potentially limb loss. Xylazine is known as "tranq" or "tranq dope" in the illicit drug market.


Xylazine can cause drowsiness, lethargy, and in rare instances, apnea and death. While xylazine is not an opioid, it is dangerous because it can depress breathing, blood pressure, heart rate and body temperature to critical levels. Additionally, people who inject drugs containing xylazine can develop severe skin wounds and patches of dead and rotting tissue that easily become infected and, if left untreated, may lead to amputation. These wounds can develop in areas of the body away from the injection site and may become life-threatening.

This story was posted on 2023-09-17 21:37:39
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